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CYP21A2 抗体 (AA 216-246)

CYP21A2 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB16954 unconjugated
产品编号 ABIN652409
发货至: 中国
  • 抗原 See all CYP21A2 抗体
    CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
    抗原表位
    • 15
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 216-246
    适用
    • 43
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 60
    克隆类型
    • 60
    多克隆
    标记
    • 27
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP21A2 antibody is un-conjugated
    应用范围
    • 35
    • 27
    • 13
    • 13
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This CYP21A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 216-246 amino acids from the Central region of human CYP21A2.
    克隆位点
    RB16954
    亚型
    Ig Fraction
    Top Product
    Discover our top product CYP21A2 Primary Antibody
  • 应用备注
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • OShaughnessy, Monteiro, Bhattacharya, Fraser, Fowler: "Steroidogenic enzyme expression in the human fetal liver and potential role in the endocrinology of pregnancy." in: Molecular human reproduction, Vol. 19, Issue 3, pp. 177-87, (2013) (PubMed).

  • 抗原
    CYP21A2 (Cytochrome P450, Family 21, Subfamily A, Polypeptide 2 (CYP21A2))
    别名
    CYP21A2 (CYP21A2 产品)
    别名
    CA21H antibody, CAH1 antibody, CPS1 antibody, CYP21 antibody, CYP21B antibody, P450c21B antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYP21A antibody, 21-OHase antibody, cytochrome P450 family 21 subfamily A member 2 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450c21 antibody, cytochrome P450, family 21, subfamily A, polypepide 2 antibody, cytochrome P450, family 21, subfamily A, polypeptide 2 antibody, steroid 21-hydroxylase-like antibody, CYP21A2 antibody, Cyp21a1 antibody, LOC101094596 antibody
    背景
    CYP21A2 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in CYP21A2 gene cause congenital adrenal hyperplasia.
    分子量
    55887
    基因ID
    1589
    NCBI登录号
    NP_000491, NP_001122062
    UniProt
    P08686
    途径
    Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process
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