Cadherin 4 抗体
Our Local Distributor
北京 101111
Quick Overview for Cadherin 4 抗体 (ABIN634764)
抗原
See all Cadherin 4 (CDH4) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity purified
-
免疫原
- CDH4 antibody was raised using a synthetic peptide corresponding to a region with amino acids RIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPL
-
-
-
-
应用备注
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
-
CDH4 Blocking Peptide, (ABIN5612783), is also available for use as a blocking control in assays to test for specificity of this CDH4 antibody
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CDH4 antibody in PBS
-
浓度
- Lot specific
-
缓冲液
- PBS
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- Cadherin 4 (CDH4)
-
别名
- CDH4
-
背景
- CDH4 gene is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
-
分子量
- 82 kDa (MW of target protein)
-
途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
-