SUV39H2 抗体
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- 抗原 See all SUV39H2 抗体
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SUV39H2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purified
- 免疫原
- SUV39 H2 antibody was raised using a synthetic peptide corresponding to a region with amino acids LDTRLPRIALFSTRTINAGEELTFDYQMKGSGDISSDSIDHSPAKKRVRT
- Top Product
- Discover our top product SUV39H2 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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SUV39H2 Blocking Peptide, catalog no. 33R-4870, is also available for use as a blocking control in assays to test for specificity of this SUV39H2 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SUV30 2 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))
- 别名
- SUV39H2 (SUV39H2 产品)
- 别名
- KMT1B antibody, 4930507K23Rik antibody, AA536750 antibody, D030054H19Rik antibody, D2Ertd544e antibody, SUV39H2 antibody, kmt1b antibody, suppressor of variegation 3-9 homolog 2 antibody, suppressor of variegation 3-9 homolog 2 (Drosophila) antibody, suppressor of variegation 3-9 homolog 2 L homeolog antibody, SUV39H2 antibody, Suv39h2 antibody, suv39h2 antibody, suv39h2.L antibody
- 背景
- SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.
- 分子量
- 40 kDa (MW of target protein)
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