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- 抗原 See all EGLN3 抗体
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EGLN3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purified
- 免疫原
- EGLN3 antibody was raised using a synthetic peptide corresponding to a region with amino acids FWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALT
- Top Product
- Discover our top product EGLN3 Primary Antibody
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anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-120) antibody
EGLN3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-239) antibodyEGLN3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-120) antibodyEGLN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 2-239) antibodyEGLN3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 1-239) antibodyEGLN3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 94-193) antibodyEGLN3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3C5 unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) antibodyEGLN3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (Internal Region) antibodyVerified EGLN3 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (AA 50-100) antibodyEGLN3 适用: 人, 大鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3) (C-Term) antibodyEGLN3 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴, 豚鼠, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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EGLN3 Blocking Peptide, catalog no. 33R-3129, is also available for use as a blocking control in assays to test for specificity of this EGLN3 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of EGLN3 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
- 别名
- EGLN3 (EGLN3 产品)
- 别名
- zgc:77019 antibody, wu:fj78a08 antibody, EGLN3 antibody, phd3 antibody, PHD-3 antibody, PHD3 antibody, SM-20 antibody, 2610021G09Rik antibody, AI505553 antibody, AI648162 antibody, Hif-p4h-3 antibody, Phd3 antibody, HIFP4H3 antibody, HIFPH3 antibody, egl-9 family hypoxia-inducible factor 3 antibody, egl-9 family hypoxia inducible factor 3 antibody, egl-9 family hypoxia-inducible factor 3 L homeolog antibody, egln3 antibody, EGLN3 antibody, egln3.L antibody, Egln3 antibody
- 背景
- EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. EGLN3 functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. EGLN3 promotes cell death through a caspase-dependent mechanism.
- 分子量
- 27 kDa (MW of target protein)
- 途径
- Positive Regulation of Endopeptidase Activity
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