EPHA2/3/4 抗体
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- 抗原 See all EPHA2/3/4 products
- EPHA2/3/4 (EPH Receptor A2/3/4 (EPHA2/3/4))
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPHA2/3/4 antibody is un-conjugated
- 应用范围
- 请咨询
- 原理
- Rabbit Anti-EPHA2/3/4 (Ab-588/596) Antibody,
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anti-EPH Receptor A2/3/4 (EPHA2/3/4) antibody
EPHA2/3/4 适用: 人, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2/3/4 (EPHA2/3/4) (Lys14) antibodyEPHA2/3/4 适用: 人, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2/3/4 (EPHA2/3/4) (pTyr588), (pTyr596) antibodyEPHA2/3/4 适用: 人, 大鼠, 小鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2/3/4 (EPHA2/3/4) (pTyr588), (pTyr596) antibodyEPHA2/3/4 适用: 人, 大鼠, 小鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2/3/4 (EPHA2/3/4) (Tyr588), (Tyr596) antibodyEPHA2/3/4 适用: 人, 大鼠 WB, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor A2/3/4 (EPHA2/3/4) (AA 556-605) antibodyEPHA2/3/4 适用: 人, 大鼠 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- EPHA2/3/4 (EPH Receptor A2/3/4 (EPHA2/3/4))
- 别名
- EPHA2/3/4 (EPHA2/3/4 产品)
- 背景
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Target Description: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand- independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
Gene Symbol: EPHA2
- 基因ID
- 1969
- UniProt
- P29317
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