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PCNA 抗体

PCNA 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6298083
发货至: 中国
  • 抗原 See all PCNA 抗体
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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    人, 小鼠, 大鼠
    宿主
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    克隆类型
    • 134
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    多克隆
    标记
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    This PCNA antibody is un-conjugated
    应用范围
    请咨询
    原理
    Rabbit Anti-PCNA Antibody,
    Top Product
    Discover our top product PCNA Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    别名
    PCNA (PCNA 产品)
    别名
    PCNAR antibody, Pcna/cyclin antibody, pcna antibody, AO090003000846 antibody, 53/13 antibody, CG9193 antibody, DmPCNA antibody, Dmel\\CG9193 antibody, MUS209 antibody, Mus209 antibody, PCNA antibody, PCNA/mus209 antibody, Pcna antibody, dPCNA antibody, l(2)02448 antibody, l(2)56F antibody, l(2)56Fa antibody, l(2)s1534 antibody, cb16 antibody, fb36g03 antibody, wu:fa28e03 antibody, wu:fb36g03 antibody, pcna-A antibody, proliferating cell nuclear antigen antibody, DNA polymerase III sliding clamp antibody, Proliferating cell nuclear antigen antibody, Proliferating cell nuclear antigen-like antibody, proliferating cell nuclear antigen L homeolog antibody, proliferating cell nuclear antigen 1 antibody, PCNA antibody, Pcna antibody, pcna antibody, MMP_RS08810 antibody, ANI_1_512014 antibody, AOR_1_1500154 antibody, MGC53867 antibody, pcna.L antibody, pcna1 antibody, LOC106420145 antibody, pcn1 antibody
    背景

    Target Description: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'- 5' exonuclease and 3'-phosphodiesterase, but not apurinic- apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.

    Gene Symbol: PCNA

    基因ID
    5111
    UniProt
    P12004
    途径
    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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