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Cyclin D2 抗体

CCND2 适用: 人, 小鼠, 大鼠 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6298006
发货至: 中国
  • 抗原 See all Cyclin D2 (CCND2) 抗体
    Cyclin D2 (CCND2)
    适用
    人, 小鼠, 大鼠
    宿主
    • 77
    • 24
    克隆类型
    • 80
    • 21
    多克隆
    标记
    • 51
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cyclin D2 antibody is un-conjugated
    应用范围
    请咨询
    原理
    Rabbit Anti-Cyclin D2 (Ab-280) Antibody,
    Top Product
    Discover our top product CCND2 Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    Cyclin D2 (CCND2)
    别名
    Cyclin D2 (CCND2 产品)
    别名
    si:ch211-240j22.2 antibody, ccnd2 antibody, CCND2 antibody, kiak0002 antibody, zgc:162280 antibody, LOC100224096 antibody, KIAK0002 antibody, BF642806 antibody, C86853 antibody, Vin-1 antibody, Vin1 antibody, cD2 antibody, 2600016F06Rik antibody, AI256817 antibody, cyclin D2, b antibody, cyclin D2 S homeolog antibody, cyclin D2 antibody, G1/S-specific cyclin-D2 antibody, cyclin D2, a antibody, cyclin D2 L homeolog antibody, ccnd2b antibody, ccnd2.S antibody, CCND2 antibody, ccnd2 antibody, ccnd2a antibody, Ccnd2 antibody, ccnd2.L antibody
    背景

    Target Description: Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).

    Gene Symbol: CCND2

    基因ID
    894
    UniProt
    P30279
    途径
    Cell Division Cycle, Mitotic G1-G1/S Phases
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