STAT6 抗体 (Biotin)
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- 抗原 See all STAT6 抗体
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This STAT6 antibody is conjugated to Biotin
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应用范围
- ELISA
- 原理
- Rabbit anti-Human Phosphorylated STAT6 Antibody [+Biotin],
- 免疫原
- This antibody was produced from antiserum of rabbits immunized with a synthetic immunogen. The IgG fraction was purified by Protein A affinity chromatography.
- Top Product
- Discover our top product STAT6 Primary Antibody
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- 应用备注
- ELISA (recommended work dilution= 1:8,000)
- 限制
- 仅限研究用
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- 溶解方式
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution . Reconstitute the antibody with diluent buffer to a final concentration of 1 mg/mL.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- -20°C
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- 抗原
- STAT6 (Signal Transducer and Activator of Transcription 6, Interleukin-4 Induced (STAT6))
- 别名
- Signal transducer and activator of transcription 6 (STAT6 产品)
- 别名
- D12S1644 antibody, IL-4-STAT antibody, STAT6B antibody, STAT6C antibody, signal transducer and activator of transcription 6 antibody, signal transducer and activator of transcription 6-like antibody, STAT6 antibody, Stat6 antibody, LOC100859543 antibody
- 背景
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Target Description: STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.Phospho-STAT6-PY is the phosphorylated form of STAT6 protein.
Gene Symbol: STAT6
- 基因ID
- 6778
- UniProt
- P42226
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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