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NEFH 抗体

NEFH 适用: 人, 大鼠, 小鼠, 小鸡, Pig IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297787
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    适用
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    人, 大鼠, 小鼠, 小鸡, Pig
    宿主
    • 67
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    • 10
    小鼠
    克隆类型
    • 83
    • 50
    单克隆
    标记
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    This NEFH antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC)
    原理
    Mouse anti-Human/Mouse/Rat/Chicken/Pig Neurofilament Heavy Antibody [IHC only]
    特异性
    Cytoplasmic
    纯化方法
    The triton-X 100 insoluble protein fraction of rat brain was used as the immunogen for this Neurofilament Heavy antibody.
    免疫原
    The triton-X 100 insoluble protein fraction of rat brain was used as the immunogen for this Neurofilament Heavy antibody.
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    Prediluted format : incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    Neurofilament heavy polypeptide (NEFH 产品)
    别名
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    背景

    Target Description: This antibody reacts with a 200 kDa protein, identified as heavy subunit of neurofilaments, or NF-H. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H), plus alpha internexin or peripherin. Each neurofilament subunit contains a globular head, an alpha helical rod domain, and variable tail domains that differ in length and amino acid content.Neurofilament antibody stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for neurofilament antibody. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.

    Gene Symbol: NEFH///KIAA0845///NFH

    基因ID
    4744
    UniProt
    P12036
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