HLA-DQA1 抗体
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- 抗原 See all HLA-DQA1 抗体
- HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
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适用
- 人, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-DQA1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 原理
- Mouse anti-Human/Pig HLA-DQ Antibody (MHC II) [Sodium Azide Free]
- 特异性
- Cell surface
- 纯化方法
- The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.
- 免疫原
- The T4-positive CTL clone HG-38 was used as the immunogen for the HLA-DQ antibody.
- Top Product
- Discover our top product HLA-DQA1 Primary Antibody
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anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 188-222), (C-Term) antibody
HLA-DQA1 适用: 人, 小鼠 WB, FACS, IF 宿主: 兔 Polyclonal RB52862 unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 24-216) antibodyHLA-DQA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 39-66) antibodyHLA-DQA1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) antibodyHLA-DQA1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 24-110) antibodyHLA-DQA1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) antibodyHLA-DQA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 39-66), (N-Term) antibodyHLA-DQA1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB32210 unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 46-74), (N-Term) antibodyHLA-DQA1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 24-213) antibody (Biotin)HLA-DQA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal Biotin
anti-Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1) (AA 24-213) antibodyHLA-DQA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT (1) - 限制
- 仅限研究用
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- 缓冲液
- In 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- HLA-DQA1 (Major Histocompatibility Complex, Class II, DQ alpha 1 (HLA-DQA1))
- 别名
- HLA class II histocompatibility antigen, DQ alpha 1 chain (HLA-DQA1 产品)
- 别名
- CD antibody, CELIAC1 antibody, DQ-A1 antibody, GSE antibody, HLA-DQA antibody, BoLA-DQA antibody, hla-dqa1 antibody, major histocompatibility complex, class II, DQ alpha 1 antibody, major histocompatibility complex, class II, DQ alpha, type 1 antibody, major histocompatibility complex, class II, DQ alpha 1 L homeolog antibody, HLA-DQA1 antibody, BOLA-DQA1 antibody, hla-dqa1.L antibody
- 背景
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Target Description: Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
Gene Symbol: HLA-DQA1///HLA-DQB1///HLA-DQB
- UniProt
- P01909, P01920
- 途径
- TCR Signaling, Cancer Immune Checkpoints
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