CD63 抗体
-
- 抗原 See all CD63 抗体
- CD63
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD63 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 原理
- Mouse anti-Human/Mouse CD63 Antibody [Sodium Azide Free]
- 特异性
- Cytoplasmic
- 纯化方法
- The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
- 免疫原
- The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
- Top Product
- Discover our top product CD63 Primary Antibody
-
-
- 应用备注
-
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - 限制
- 仅限研究用
-
- 缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
- 抗原
- CD63
- 别名
- CD63 antigen (CD63 产品)
- 别名
- C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody
- 背景
-
Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Gene Symbol: CD63///MLA1///TSPAN30
- 基因ID
- 967
- UniProt
- P08962
-