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CD63 抗体

CD63 适用: 人 FACS, IHC, IF 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297772
发货至: 中国
  • 抗原 See all CD63 抗体
    CD63
    适用
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    宿主
    • 76
    • 63
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    小鼠
    克隆类型
    • 97
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    单克隆
    标记
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    This CD63 antibody is un-conjugated
    应用范围
    • 91
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    原理
    Mouse anti-Human CD63 Antibody Cocktail [Sodium Azide Free]
    特异性
    Cytoplasmic
    纯化方法
    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
    免疫原
    The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
    Top Product
    Discover our top product CD63 Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD63
    别名
    CD63 antigen (CD63 产品)
    别名
    C75951 antibody, ME491 antibody, Tspan30 antibody, LAMP-3 antibody, MLA1 antibody, OMA81H antibody, TSPAN30 antibody, TSP29FA antibody, CD63 antigen antibody, CD63 molecule antibody, Cd63 molecule antibody, Cd63 antibody, CD63 antibody
    背景

    Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

    Gene Symbol: CD63///MLA1///TSPAN30

    基因ID
    967
    UniProt
    P08962
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