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CD45 抗体 (PE)

PTPRC 适用: 人 FACS, IF, T 宿主: 小鼠 Monoclonal PE
产品编号 ABIN6297769
发货至: 中国
  • 抗原 See all CD45 (PTPRC) 抗体
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD45 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
    原理
    Mouse anti-Human CD45RB Antibody [PE Conjugated]
    特异性
    Cell surface and cytoplasmic
    纯化方法
    The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody.
    免疫原
    The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody.
    Top Product
    Discover our top product PTPRC Primary Antibody
  • 应用备注
    Flow Cytometry: 5 µL/test/10e6 cells in 100 µL (or 5 µL per 100 µL of whole blood)
    Immunofluorescence: 1:50-1:100
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C. The conjugate is light-sensitive, protect from light.
  • 抗原
    CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
    别名
    Receptor-type tyrosine-protein phosphatase C (PTPRC 产品)
    别名
    PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody
    背景

    Target Description: CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. antibody to CD45R is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.

    Gene Symbol: PTPRC///CD45

    基因ID
    5788
    UniProt
    P08575
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling
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