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CD3 epsilon 抗体

CD3E 适用: 人, 猴 FACS, IF, Act, Func, ProA 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297680
发货至: 中国
  • 抗原 See all CD3 epsilon (CD3E) 抗体
    CD3 epsilon (CD3E)
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    人, 猴
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD3 epsilon antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Activation (Act), Functional Studies (Func), Proliferation Assay (ProA)
    原理
    Mouse anti-Human/Monkey CD3e Antibody [Sodium Azide Free]
    特异性
    Cell surface and cytoplasmic
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the CD3e antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD3e antibody.
    Top Product
    Discover our top product CD3E Primary Antibody
  • 应用备注
    Functional Activity: Induce T cell activation and proliferation (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD3 epsilon (CD3E)
    别名
    T-cell surface glycoprotein CD3 epsilon chain (CD3E 产品)
    别名
    cd3e antibody, CD3E antibody, t3e antibody, tcre antibody, AI504783 antibody, CD3 antibody, CD3epsilon antibody, T3e antibody, T3E antibody, TCRE antibody, CD3e molecule antibody, CD3 antigen, epsilon polypeptide antibody, cd3e antibody, CD3E antibody, Cd3e antibody
    背景

    Target Description: Recognizes the epsilon-chain of CD3 (Workshop V, Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

    Gene Symbol: CD3E///T3E

    基因ID
    916
    UniProt
    P07766
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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