FNTA 抗体 (Center)
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- 抗原 See all FNTA 抗体
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
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抗原表位
- AA 88-118, Center
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FNTA antibody is un-conjugated
- 应用范围
- 请咨询
- 原理
- Rabbit Anti-FNTA (Center) Antibody
- 免疫原
- This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.
- Top Product
- Discover our top product FNTA Primary Antibody
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- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C (short-term), -20°C (long-term)
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- 抗原
- FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
- 别名
- FNTA (FNTA 产品)
- 别名
- ATFTA antibody, FARNESYLTRANSFERASE A antibody, FARNESYLTRANSFERASE SUBUNIT A antibody, PFT/PGGT-IALPHA antibody, PLP antibody, PLURIPETALA antibody, farnesyltransferase A antibody, FPTA antibody, PGGT1A antibody, PTAR2 antibody, PFAS antibody, FTA antibody, farnesyltransferase A antibody, farnesyltransferase, CAAX box, alpha antibody, FTA antibody, FNTA antibody, Fnta antibody
- 背景
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Target Description: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.
Gene Symbol: FNTA
- 基因ID
- 2339
- UniProt
- P49354
- 途径
- Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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