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FNTA 抗体 (Center)

FNTA 适用: 人, 小鼠 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6295422
发货至: 中国
  • 抗原 See all FNTA 抗体
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 88-118, Center
    适用
    • 51
    • 26
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 49
    • 2
    克隆类型
    • 50
    • 1
    多克隆
    标记
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FNTA antibody is un-conjugated
    应用范围
    请咨询
    原理
    Rabbit Anti-FNTA (Center) Antibody
    免疫原
    This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-118 amino acids from the Central region of human FNTA.
    Top Product
    Discover our top product FNTA Primary Antibody
  • 限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    2-8°C (short-term), -20°C (long-term)
  • 抗原
    FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))
    别名
    FNTA (FNTA 产品)
    别名
    ATFTA antibody, FARNESYLTRANSFERASE A antibody, FARNESYLTRANSFERASE SUBUNIT A antibody, PFT/PGGT-IALPHA antibody, PLP antibody, PLURIPETALA antibody, farnesyltransferase A antibody, FPTA antibody, PGGT1A antibody, PTAR2 antibody, PFAS antibody, FTA antibody, farnesyltransferase A antibody, farnesyltransferase, CAAX box, alpha antibody, FTA antibody, FNTA antibody, Fnta antibody
    背景

    Target Description: FNTA, also known as CAAX farnesyltransferase (FTase), attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain. This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence. FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors. It is likely to be a key component of the signaling pathway which involves p21ras, an important substrate for farnesyltransferase.

    Gene Symbol: FNTA

    基因ID
    2339
    UniProt
    P49354
    途径
    Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling
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