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- 抗原 See all TYROBP 抗体
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TYROBP antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human TYROBP
- 亚型
- IgG
- Top Product
- Discover our top product TYROBP Primary Antibody
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anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) antibody
TYROBP 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (C-Term) antibodyTYROBP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) antibodyTYROBP 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22347 unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 84-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113), (C-Term) antibodyTYROBP 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 31-113) antibody (PE)TYROBP 适用: 小鼠 WB, FACS 宿主: 兔 Polyclonal PE
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) antibodyTYROBP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (Cytoplasmic Domain) antibodyTYROBP 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-TYRO Protein tyrosine Kinase Binding Protein (TYROBP) (AA 85-113) antibodyTYROBP 适用: 人 WB, FACS, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500 - 1:2000
- 说明
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Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes, Expressed in hematological cells and tissues such as peripheral blood leukocytes and spleen, Also found in bone marrow, lymph nodes, placenta, lung and liver, Expressed at lower levels in different parts of the brain especially in the basal ganglia and corpus callosum
- 限制
- 仅限研究用
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- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20C. Avoid freeze / thaw cycles.
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- 抗原
- TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
- 别名
- TYROBP (TYROBP 产品)
- 别名
- TYROBP antibody, DAP12 antibody, tyrpbp antibody, Karap antibody, KARAP antibody, PLOSL antibody, Ly83 antibody, dap12 antibody, TYRO protein tyrosine kinase binding protein antibody, Tyro protein tyrosine kinase binding protein antibody, TYROBP antibody, tyrobp antibody, Tyrobp antibody
- 背景
- This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.
- 分子量
- 12.179 kDa
- 基因ID
- 7305
- UniProt
- O43914
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