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ADRB3 抗体 (Internal Region)

ADRB3 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6282314
发货至: 中国
  • 抗原 See all ADRB3 抗体
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    抗原表位
    • 15
    • 15
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-300, Internal Region
    适用
    • 54
    • 36
    • 24
    • 1
    人, 大鼠, 小鼠
    宿主
    • 52
    • 2
    • 2
    • 2
    克隆类型
    • 58
    多克隆
    标记
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ADRB3 antibody is un-conjugated
    应用范围
    • 45
    • 26
    • 26
    • 17
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    AR-β3 is a protein encoded by the ADRB3 gene which is approximately 43,5 kDa. AR-β3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-β3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-β3 protein.
    特异性
    AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.
    产品特性
    Rabbit polyclonal to AR-β3.
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized peptide derived from human AR-beta3
    亚型
    IgG
    Top Product
    Discover our top product ADRB3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    ELISA 1:20000
    说明

    Expressed mainly in adipose tissues.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原
    ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
    别名
    AR-beta3 (ADRB3 产品)
    别名
    BETA3AR antibody, Adrb-3 antibody, ADRB antibody, BAR3 antibody, B3AR antibody, GPCR antibody, im:7154935 antibody, si:ch211-215f19.1 antibody, zgc:194843 antibody, zgc:194852 antibody, adrenoceptor beta 3 antibody, adrenergic receptor, beta 3 antibody, adrenoceptor beta 3a antibody, adrenoceptor beta 3b antibody, ADRB3 antibody, Adrb3 antibody, adrb3a antibody, adrb3b antibody
    分子量
    36 kDa
    基因ID
    155
    UniProt
    P13945
    途径
    cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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