FZD2 抗体 (Internal Region)
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- 抗原 See all FZD2 抗体
- FZD2 (Frizzled Family Receptor 2 (FZD2))
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抗原表位
- AA 180-260, Internal Region
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FZD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 原理
- Frizzled-2 is a protein encoded by the FZD2 gene which is approximately 63,5 kDa. Frizzled-2 is localised to the cell membrane and is involved in CDK-mediated phosphorylation and removal of Cdc6, Wnt signalling pathway and pluripotency and mTOR signalling pathway. It is a receptor for Wnt proteins and is coupled to the beta-catenin canonical signalling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Frizzled-2 is widely expressed, it is mainly found in heart, placenta, skeletal muscle, lung, kidney, pancreas, prostate, testis, ovary and colon. Mutations in the FZD2 gene result in omodysplasia. STJ93141 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Frizzled-2 protein.
- 特异性
- Frizzled-2 Polyclonal Antibody detects endogenous levels of Frizzled-2 protein.
- 产品特性
- Rabbit polyclonal to Frizzled-2.
- 纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 免疫原
- Synthesized peptide derived from human Frizzled-2
- 亚型
- IgG
- Top Product
- Discover our top product FZD2 Primary Antibody
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anti-Frizzled Family Receptor 2 (FZD2) (Internal Region) antibody
Verified FZD2 适用: 人 WB, ELISA, IF, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (Extracellular Domain) antibodyFZD2 适用: 人, 大鼠, 小鼠, 马, Cow, 犬, Hamster, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 192-245) antibodyFZD2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C8 unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (Internal Region) antibodyFZD2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, 马, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) antibodyFZD2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, 马, Cow, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (N-Term) antibodyFZD2 适用: 人, 大鼠, 小鼠, 马, Cow, 犬, Hamster, Pig, 猴, 兔, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 201-250) antibodyFZD2 适用: 人, 大鼠, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 2 (FZD2) (AA 192-205), (Extracellular), (N-Term) antibodyFZD2 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000 - 说明
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Widely expressed. In the adult, mainly found in heart, placenta, skeletal muscle, lung, kidney, pancreas, prostate, testis, ovary and colon. In the fetus, expressed in brain, lung and kidney. Low levels in fetal liver.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- 抗原
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 别名
- Frizzled-2 (FZD2 产品)
- 别名
- BG01711 antibody, CG9739 antibody, D-Fz2 antibody, D-fz2 antibody, DFZ2 antibody, DFz-2 antibody, DFz2 antibody, Dfrz2 antibody, Dfz2 antibody, Dfz[[2]] antibody, Dm Fz2 antibody, Dmel\\CG9739 antibody, FZ2 antibody, Fz2 antibody, dFz2 antibody, dfz(2) antibody, dfz2 antibody, dfz2r antibody, frz2 antibody, fz-2 antibody, fz8 antibody, zfz2 antibody, zg08 antibody, cb383 antibody, wu:fb70g09 antibody, FZD2 antibody, fzE2 antibody, hFz2 antibody, Fz-10 antibody, Fzd10 antibody, cFz-2 antibody, frizzled2 antibody, fz2 antibody, xfz2 antibody, AL033370 antibody, AW456835 antibody, Fz10 antibody, Mfz10 antibody, Mfz10a antibody, frizzled 2 antibody, frizzled class receptor 2 antibody, frizzled class receptor 2 S homeolog antibody, fz2 antibody, fzd2 antibody, FZD2 antibody, Fzd2 antibody, fzd2.S antibody
- 分子量
- 55 kDa
- 基因ID
- 2535
- UniProt
- Q14332
- 途径
- WNT signaling
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