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- 抗原 See all CUBN 抗体
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CUBN antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)
- 特异性
- Cubilin Antibody detects endogenous levels of total Cubilin.
- 预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Cubilin, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CUBN Primary Antibody
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anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) antibody
CUBN 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 51-150) antibodyCUBN 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (N-Term) antibodyCUBN 适用: 人 WB, IHC, ICC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 98-207) antibodyCUBN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3157-3274) antibodyCUBN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN) (AA 3511-3623) antibodyCUBN 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CUBN (Cubilin (Intrinsic Factor-Cobalamin Receptor) (CUBN))
- 别名
- CUBN (CUBN 产品)
- 别名
- GP280 antibody, IFCR antibody, MGA1 antibody, AA408369 antibody, AL022750 antibody, D2Wsu88e antibody, gp280 antibody, cubilin antibody, cubilin (intrinsic factor-cobalamin receptor) antibody, LOC411053 antibody, CUBN antibody, cubn antibody, Cubn antibody
- 背景
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Description: Cotransporter which plays a role in lipoprotein, vitamin and iron metabolism, by facilitating their uptake. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the GIF-cobalamin complex. The binding of all ligands requires calcium. Serves as important transporter in several absorptive epithelia, including intestine, renal proximal tubules and embryonic yolk sac. Interaction with LRP2 mediates its trafficking throughout vesicles and facilitates the uptake of specific ligands like GC, hemoglobin, ALB, TF and SCGB1A1. Interaction with AMN controls its trafficking to the plasma membrane and facilitates endocytosis of ligands. May play an important role in the development of the peri-implantation embryo through internalization of APOA1 and cholesterol. Binds to LGALS3 at the maternal-fetal interface.
Gene: CUBN
- 分子量
- 399kDa
- 基因ID
- 8029
- UniProt
- O60494
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Lipid Metabolism
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