XRCC3 抗体 (N-Term)
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- 抗原 See all XRCC3 抗体
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XRCC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- XRCC3 Antibody detects endogenous levels of total XRCC3.
- 预测反应
- Bovine
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human XRCC3, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product XRCC3 Primary Antibody
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (AA 62-346) antibody
XRCC3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (AA 1-346) antibodyXRCC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (N-Term) antibodyXRCC3 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (AA 41-90) antibodyXRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (AA 41-90) antibodyXRCC3 适用: 人 ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) antibodyXRCC3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (C-Term) antibodyXRCC3 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) antibodyXRCC3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) (Internal Region) antibodyXRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3) antibodyXRCC3 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal 10F1-6 unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- 别名
- XRCC3 (XRCC3 产品)
- 背景
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Description: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD21 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, CX3 acts downstream of RAD51 recruitment, the complex binds predominantly to the intersection of the four duplex arms of the Holliday junction (HJ) and to junctions of replication forks. Involved in HJ resolution and thus in processing HR intermediates late in the DNA repair process, the function may be linked to the CX3 complex and seems to involve GEN1 during mitotic cell cycle progression. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C.
Gene: XRCC3
- 分子量
- 38kDa
- 基因ID
- 7517
- UniProt
- O43542
- 途径
- DNA Damage Repair
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