WNT7A 抗体 (Internal Region)
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- 抗原 See all WNT7A 抗体
- WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNT7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Wnt7a Antibody detects endogenous levels of total Wnt7a.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Wnt7a, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product WNT7A Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))
- 别名
- WNT7A (WNT7A 产品)
- 别名
- wnt7a antibody, AI849442 antibody, Wnt-7a antibody, px antibody, tw antibody, Xwnt-7a antibody, wnt-7a antibody, wnt7a-A antibody, Wnt family member 7A antibody, wingless-type MMTV integration site family, member 7Aa antibody, wingless-type MMTV integration site family, member 7A antibody, wingless-type MMTV integration site family member 7A S homeolog antibody, WNT7A antibody, wnt7aa antibody, Wnt7a antibody, wnt7a.S antibody
- 背景
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Description: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. Promotes formation of synapses via its interaction with FZD5 (By similarity).
Gene: WNT7A
- 分子量
- 39kDa
- 基因ID
- 7476
- UniProt
- O00755
- 途径
- WNT signaling, Stem Cell Maintenance, Asymmetric Protein Localization
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