SPOP-B 抗体 (Internal Region)
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- 抗原 See all SPOP-B 抗体
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPOP-B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- SPOP Antibody detects endogenous levels of total SPOP.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SPOP, corresponding to a region within the internal amino acids.
- 亚型
- IgG
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anti-Speckle-Type POZ Protein (SPOP-B) (AA 301-374) antibody
SPOP-B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E2 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (Center) antibodySPOP-B 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 48-374) antibodySPOP-B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 74-107), (N-Term) antibodySPOP-B 适用: 小鼠, 斑马鱼 WB 宿主: 兔 Polyclonal RB49885 unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-374) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (C-Term) antibodySPOP-B 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 兔, 豚鼠, 马, 非洲爪蟾, 小鸡, Hamster, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 1-193) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Speckle-Type POZ Protein (SPOP-B) (AA 175-374) antibodySPOP-B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- 别名
- SPOP (SPOP-B 产品)
- 别名
- BTBD32 antibody, TEF2 antibody, AI315626 antibody, Pcif1 antibody, zgc:64140 antibody, spop antibody, tef2 antibody, speckle type BTB/POZ protein antibody, speckle-type POZ protein antibody, speckle type POZ protein S homeolog antibody, SPOP antibody, Spop antibody, spop antibody, spop.S antibody
- 背景
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Description: Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1, this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
Gene: SPOP
- 分子量
- 42 kDa
- 基因ID
- 8405
- UniProt
- O43791
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