-
- 抗原 See all RBPJ 抗体
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RBPJ antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- RBPJ Antibody detects endogenous levels of total RBPJ.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human RBPJ, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product RBPJ Primary Antibody
-
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibody
RBPJ 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-29) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 101-200) antibodyRBPJ 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 243-485) antibodyRBPJ 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibodyRBPJ 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-487) antibodyRBPJ 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 3-109) antibodyRBPJ 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (C-Term) antibodyRBPJ 适用: 人, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, 非洲爪蟾, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) (AA 1-260) antibodyRBPJ 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ) antibodyRBPJ 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
- 别名
- RBPJ (RBPJ 产品)
- 别名
- AOS3 antibody, CBF1 antibody, IGKJRB antibody, IGKJRB1 antibody, KBF2 antibody, RBP-J antibody, RBPJK antibody, RBPSUH antibody, SUH antibody, csl antibody, AI843960 antibody, Igkjrb antibody, Igkrsbp antibody, RBP-J kappa antibody, RBPjk antibody, Rbpsuh antibody, Su(H) antibody, XSu(H) antibody, xsu(h)1 antibody, Su(H)1 antibody, Su(h)A antibody, ik:tdsubc_1e8 antibody, rbpj antibody, rbpsuh antibody, xx:tdsubc_1e8 antibody, Su(H)2 antibody, su(h)B antibody, recombination signal binding protein for immunoglobulin kappa J region antibody, recombination signal binding protein for immunoglobulin kappa J region S homeolog antibody, recombination signal binding protein for immunoglobulin kappa J region a antibody, recombination signal binding protein for immunoglobulin kappa J region b antibody, RBPJ antibody, Rbpj antibody, rbpj.S antibody, rbpja antibody, rbpjb antibody
- 背景
-
Description: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA (PubMed:21991380). Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4 % oxygen) (PubMed:23303788). Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits (By similarity).
Gene: RBPJ
- 分子量
- 55kDa
- 基因ID
- 3516
- UniProt
- Q06330
- 途径
- Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
-
You are here:
