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PTPRB 抗体 (N-Term)

PTPRB 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264522
发货至: 中国
  • 抗原 See all PTPRB 抗体
    PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 小鼠
    宿主
    • 14
    • 1
    • 1
    克隆类型
    • 15
    • 1
    多克隆
    标记
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PTPRB antibody is un-conjugated
    应用范围
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    PTPRB Antibody detects endogenous levels of total PTPRB.
    预测反应
    Pig,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PTPRB, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product PTPRB Primary Antibody
  • 应用备注
    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    PTPRB (Protein tyrosine Phosphatase, Receptor Type, B (PTPRB))
    别名
    PTPRB (PTPRB 产品)
    别名
    PTPRB antibody, HPTP-BETA antibody, HPTPB antibody, PTPB antibody, R-PTP-BETA antibody, VEPTP antibody, 3230402H02Rik antibody, C130094E24 antibody, Ptpz antibody, Rptpb antibody, VE-PTP antibody, Veptp antibody, protein tyrosine phosphatase, receptor type B antibody, receptor-type tyrosine-protein phosphatase beta antibody, protein tyrosine phosphatase, receptor type, B antibody, PTPRB antibody, LOC100380677 antibody, Ptprb antibody
    背景

    Description: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothelial cells and this requires the presence of plakoglobin (By similarity).

    Gene: PTPRB

    分子量
    224kDa
    基因ID
    5787
    UniProt
    P23467
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