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PPP1CB 抗体

PPP1CB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264381
发货至: 中国
  • 抗原 See all PPP1CB 抗体
    PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
    适用
    • 66
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    人, 小鼠, 大鼠
    宿主
    • 61
    • 8
    • 4
    • 1
    克隆类型
    • 69
    • 5
    多克隆
    标记
    • 42
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    This PPP1CB antibody is un-conjugated
    应用范围
    • 52
    • 40
    • 10
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    • 1
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    特异性
    PPP1CB Antibody detects endogenous levels of total PPP1CB
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PPP1CB
    亚型
    IgG
    Top Product
    Discover our top product PPP1CB Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
    别名
    PPP1CB (PPP1CB 产品)
    别名
    PP-1B antibody, PP1B antibody, PP1beta antibody, PPP1CD antibody, 1200010B19 antibody, ik:tdsubc_2f2 antibody, si:zc214p16.4 antibody, wu:fa09h01 antibody, wu:fa11e06 antibody, xx:tdsubc_2f2 antibody, PP2CB antibody, Ppp1cb antibody, protein phosphatase 1 catalytic subunit beta antibody, protein phosphatase 1, catalytic subunit, beta isoform antibody, protein phosphatase 1, catalytic subunit, beta isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, protein phosphatase 1B, magnesium dependent, beta isoform antibody, PPP1CB antibody, Ppp1cb antibody, ppp1cb.L antibody, ppp1cb antibody, LOC100224238 antibody, Ppm1b antibody
    背景

    Description: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).

    Gene: PPP1CB

    分子量
    37kDa
    基因ID
    5500
    UniProt
    P62140
    途径
    M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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