电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Nth Endonuclease III-Like 1 (NTHL1) 抗体

NTHL1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6263755
发货至: 中国
  • 抗原 See all Nth Endonuclease III-Like 1 (NTHL1) 抗体
    Nth Endonuclease III-Like 1 (NTHL1)
    适用
    • 42
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 46
    • 1
    克隆类型
    • 45
    • 2
    多克隆
    标记
    • 20
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    非结合性
    应用范围
    • 31
    • 27
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    NTHL1 Antibody detects endogenous levels of total NTHL1
    交叉反应
    人, 小鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human NTHL1
    亚型
    IgG
    Top Product
    Discover our top product NTHL1 Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    Nth Endonuclease III-Like 1 (NTHL1)
    别名
    NTHL1 (NTHL1 产品)
    别名
    psmc3 antibody, psmc3-a antibody, nth-like DNA glycosylase 1 S homeolog antibody, nthl1.S antibody
    背景

    Description: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

    Gene: NTHL1

    分子量
    34 kDa
    基因ID
    4913
    UniProt
    P78549
You are here:
客服