NFKBIZ 抗体 (Internal Region)
-
- 抗原 See all NFKBIZ 抗体
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This NFKBIZ antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- NFKBIZ Antibody detects endogenous levels of total NFKBIZ.
- 预测反应
- Bovine,Horse,Sheep,Rabbit
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NFKBIZ, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NFKBIZ Primary Antibody
-
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- NFKBIZ (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, zeta (NFKBIZ))
- 别名
- NFKBIZ (NFKBIZ 产品)
- 别名
- RGD1310834 antibody, NFKBIZ antibody, MAIL antibody, AA408868 antibody, INAP antibody, Mail antibody, IKBZ antibody, NFKB inhibitor zeta antibody, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta antibody, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta antibody, Nfkbiz antibody, NFKBIZ antibody, nfkbiz antibody
- 背景
-
Description: Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis (By similarity).
Gene: NFKBIZ
- 分子量
- 64 kDa
- 基因ID
- 64332
- UniProt
- Q9BYH8
- 途径
- NF-kappaB Signaling
-