NEIL2 抗体 (Internal Region)
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- 抗原 See all NEIL2 抗体
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEIL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
- 特异性
- NEIL2 Antibody detects endogenous levels of total NEIL2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NEIL2, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NEIL2 Primary Antibody
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anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibody
NEIL2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibodyNEIL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
- 别名
- NEIL2 (NEIL2 产品)
- 别名
- NEH2 antibody, NEI2 antibody, Gm1212 antibody, nei like DNA glycosylase 2 antibody, nei like 2 (E. coli) antibody, NEIL2 antibody, Neil2 antibody
- 背景
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Description: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Gene: NEIL2
- 分子量
- 37 kDa
- 基因ID
- 252969
- UniProt
- Q969S2
- 途径
- DNA Damage Repair
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