LGALS8 抗体 (Internal Region)
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- 抗原 See all LGALS8 抗体
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGALS8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- Galectin 8 Antibody detects endogenous levels of total Galectin 8.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Galectin 8, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LGALS8 Primary Antibody
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anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 1-317) antibody
LGALS8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 1-358) antibodyLGALS8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 271-298), (C-Term) antibodyLGALS8 适用: 人 WB 宿主: 兔 Polyclonal RB20572 unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 1-316) antibodyLGALS8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 151-316) antibodyLGALS8 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 20-317) antibodyLGALS8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) antibodyLGALS8 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (Center) antibodyLGALS8 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (AA 281-359) antibodyLGALS8 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) (Internal Region) antibodyLGALS8 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- LGALS8 (Lectin, Galactoside-Binding, Soluble, 8 (LGALS8))
- 别名
- LGALS8 (LGALS8 产品)
- 别名
- LGALS8 antibody, 1200015E08Rik antibody, AI326142 antibody, D13Ertd524e antibody, Lgals-8 antibody, galectin-8 antibody, Gal-8 antibody, PCTA-1 antibody, PCTA1 antibody, Po66-CBP antibody, xgalectin-VIIIa antibody, galectin 8 antibody, lectin, galactose binding, soluble 8 antibody, lectin, galactoside binding soluble 8 S homeolog antibody, LGALS8 antibody, Lgals8 antibody, lgals8.S antibody
- 背景
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Description: Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy (PubMed:22246324, PubMed:28077878). Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane, these ligands becoming exposed to the cytoplasm following rupture (PubMed:22246324, PubMed:28077878). Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52 (PubMed:22246324, PubMed:28077878). Required to restrict infection of bacterial invasion such as S.typhimurium (PubMed:22246324). Also required to restrict infection of Picornaviridae viruses (PubMed:28077878). Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans (PubMed:21288902).
Gene: LGALS8
- 分子量
- 40 kDa
- 基因ID
- 3964
- UniProt
- O00214
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