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CEMIP 抗体 (C-Term)

CEMIP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262798
发货至: 中国
  • 抗原 See all CEMIP 抗体
    CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
    抗原表位
    • 15
    • 15
    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 41
    • 35
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 4
    克隆类型
    • 48
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This CEMIP antibody is un-conjugated
    应用范围
    • 48
    • 26
    • 26
    • 16
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    KIAA1199 Antibody detects endogenous levels of total KIAA1199.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human KIAA1199, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CEMIP Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CEMIP (Cell Migration Inducing Hyaluronan Binding Protein (CEMIP))
    别名
    CEMIP (CEMIP 产品)
    别名
    CCSP1 antibody, TMEM2L antibody, 3110012M15Rik antibody, mKIAA1412 antibody, 12H19.01.T7 antibody, 6330404C01Rik antibody, AY007814 antibody, Kiaa1199 antibody, KIAA1199 antibody, cell migration inducing hyaluronan binding protein antibody, transmembrane protein 2 antibody, cell migration inducing protein, hyaluronan binding antibody, CEMIP antibody, Tmem2 antibody, TMEM2 antibody, Cemip antibody
    背景

    Description: Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner. May be involved in hearing.

    Gene: CEMIP

    分子量
    153 kDa
    基因ID
    57214
    UniProt
    Q8WUJ3
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