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KRT17 抗体 (C-Term)

KRT17 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262776
发货至: 中国
  • 抗原 See all KRT17 抗体
    KRT17 (Keratin 17 (KRT17))
    抗原表位
    • 15
    • 15
    • 12
    • 11
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    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 122
    • 46
    • 28
    • 18
    • 13
    • 11
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    • 1
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    • 1
    人, 大鼠, 小鼠
    宿主
    • 98
    • 35
    克隆类型
    • 86
    • 47
    多克隆
    标记
    • 55
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KRT17 antibody is un-conjugated
    应用范围
    • 101
    • 43
    • 37
    • 30
    • 27
    • 26
    • 22
    • 20
    • 18
    • 14
    • 10
    • 3
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)
    特异性
    Cytokeratin 17 Antibody detects endogenous levels of total Cytokeratin 17.
    预测反应
    Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Cytokeratin 17, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product KRT17 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC: 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    KRT17 (Keratin 17 (KRT17))
    别名
    KRT17 (KRT17 产品)
    别名
    K17 antibody, Krt1-17 antibody, PC antibody, PC2 antibody, PCHC1 antibody, Ka17 antibody, KRT17 antibody, krt16 antibody, si:dkeyp-113d7.7 antibody, KRT14 antibody, keratin 17 antibody, keratin 17 L homeolog antibody, keratin 17, type I antibody, keratin, type I cytoskeletal 17 antibody, Krt17 antibody, KRT17 antibody, krt17 antibody, krt17.L antibody, LOC100737113 antibody, LOC102177275 antibody
    背景

    Description: Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.

    Gene: KRT17

    分子量
    48kDa
    基因ID
    3872
    UniProt
    Q04695
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