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IRS1 抗体

IRS1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262666
发货至: 中国
  • 抗原 See all IRS1 抗体
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    适用
    • 292
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    人, 小鼠, 大鼠, 猴
    宿主
    • 292
    • 12
    克隆类型
    • 285
    • 19
    多克隆
    标记
    • 138
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    This IRS1 antibody is un-conjugated
    应用范围
    • 172
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    • 24
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    • 7
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    IRS-1 Antibody detects endogenous levels of total IRS-1
    交叉反应
    人, 猴, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human IRS-1
    亚型
    IgG
    Top Product
    Discover our top product IRS1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • Li, Feng, Wei, Liu, Yang, Hou, Zhao, Zhang, Yang: "The Aqueous Extract of Gynura divaricata (L.) DC. Improves Glucose and Lipid Metabolism and Ameliorates Type 2 Diabetes Mellitus." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 8686297, (2018) (PubMed).

    Tian, Liu, Wang, Dong, Su, Ma, Zhang: "Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats." in: Life sciences, Vol. 150, pp. 1-7, (2016) (PubMed).

  • 抗原
    IRS1 (Insulin Receptor Substrate 1 (IRS1))
    别名
    IRS-1 (IRS1 产品)
    别名
    HIRS-1 antibody, G972R antibody, IRS-1 antibody, IRS1IRM antibody, irs1 antibody, irsu antibody, IRS1 antibody, irs-1 antibody, irs1-a antibody, insulin receptor substrate 1 antibody, insulin receptor substrate 2 antibody, insulin receptor substrate 1 S homeolog antibody, IRS1 antibody, Irs1 antibody, irs2 antibody, irs1.S antibody
    背景

    Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

    Gene: IRS1

    分子量
    180kDa
    基因ID
    3667
    UniProt
    P35568
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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