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- 抗原 See all INSIG2 抗体
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INSIG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- INSIG2 Antibody detects endogenous levels of total INSIG2.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human INSIG2, corresponding to a region within N-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product INSIG2 Primary Antibody
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anti-Insulin Induced Gene 2 (INSIG2) (AA 50-150) antibody
INSIG2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) antibodyINSIG2 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 兔, Cow, 山羊, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Insulin Induced Gene 2 (INSIG2) (N-Term) antibodyINSIG2 适用: 人, 小鼠, 大鼠, 兔, Cow, 山羊, 马, Pig, 犬, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- INSIG2 (Insulin Induced Gene 2 (INSIG2))
- 别名
- INSIG2 (INSIG2 产品)
- 别名
- MGC82156 antibody, INSIG-2 antibody, 2900053I11Rik antibody, C730043J18Rik antibody, Insig-2 antibody, insulin induced gene 2 antibody, insulin induced gene 2 L homeolog antibody, insig2 antibody, insig2.L antibody, INSIG2 antibody, Insig2 antibody
- 背景
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Description: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.
Gene: INSIG2
- 分子量
- 25 kDa
- 基因ID
- 51141
- UniProt
- Q9Y5U4
- 途径
- ER-Nucleus Signaling
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