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GRB7 抗体 (Internal Region)

GRB7 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6262079
发货至: 中国
  • 抗原 See all GRB7 抗体
    GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 59
    • 15
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 56
    • 3
    • 1
    • 1
    克隆类型
    • 60
    • 1
    多克隆
    标记
    • 30
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRB7 antibody is un-conjugated
    应用范围
    • 36
    • 27
    • 13
    • 13
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    GRB7 Antibody detects endogenous levels of total GRB7.
    预测反应
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human GRB7, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product GRB7 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    GRB7 (Growth Factor Receptor-Bound Protein 7 (GRB7))
    别名
    GRB7 (GRB7 产品)
    别名
    GRB7 antibody, mKIAA4028 antibody, growth factor receptor bound protein 7 antibody, GRB7 antibody, Grb7 antibody
    背景

    Description: Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

    Gene: GRB7

    分子量
    60 kDa
    基因ID
    2886
    UniProt
    Q14451
    途径
    EGFR Signaling Pathway, Ribonucleoprotein Complex Subunit Organization
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