-
- 抗原 See all FZD5 抗体
- FZD5 (Frizzled Family Receptor 5 (FZD5))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This FZD5 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- FZD5 Antibody detects endogenous levels of total FZD5.
- 预测反应
- Pig,Bovine,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human FZD5, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product FZD5 Primary Antibody
-
anti-Frizzled Family Receptor 5 (FZD5) (AA 72-161) antibody
FZD5 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 6A3 unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 151-217) antibodyFZD5 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (N-Term) antibodyFZD5 适用: 人, 小鼠, 大鼠, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (Cytoplasmic Domain) antibodyFZD5 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 461-510) antibodyFZD5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 467-516) antibodyFZD5 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 72-161) antibodyFZD5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 1-585) antibodyFZD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) antibodyFZD5 适用: 人, Cow, 犬, 兔, Pig, 猴, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 5 (FZD5) (AA 130-240) antibodyFZD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- FZD5 (Frizzled Family Receptor 5 (FZD5))
- 别名
- FZD5 (FZD5 产品)
- 别名
- C2orf31 antibody, HFZ5 antibody, 5330434N09Rik antibody, AI427138 antibody, Fz-5 antibody, Fz5 antibody, mFz5 antibody, Xfz5 antibody, frizzled5 antibody, frizzled5a antibody, fz5 antibody, fzd5-A antibody, fz2 antibody, fz8c antibody, fzd8c antibody, zg02 antibody, frizzled class receptor 5 antibody, frizzled class receptor 5 S homeolog antibody, FZD5 antibody, Fzd5 antibody, fzd5.S antibody, fzd5 antibody
- 背景
-
Description: Receptor for Wnt proteins (PubMed:9054360, PubMed:10097073, PubMed:20530549). Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro), the in vivo situation may be different since not all of these are known to be coexpressed (By similarity). In neurons, activation of WNT7A promotes formation of synapses (PubMed:20530549). Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity). A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization (By similarity).
Gene: FZD5
- 分子量
- 64 kDa
- 基因ID
- 7855
- UniProt
- Q13467
- 途径
- WNT signaling
-
You are here:
