-
- 抗原 See all CLP1 抗体
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CLP1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- CLP1 Antibody detects endogenous levels of total CLP1
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CLP1
- 亚型
- IgG
- Top Product
- Discover our top product CLP1 Primary Antibody
-
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (Center) antibody
CLP1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D5 unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
-
- 应用备注
- WB 1:1000-3000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 有效期
- 12 months
-
- 抗原
- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
- 别名
- CLP1 (CLP1 产品)
- 别名
- Heab antibody, RGD1307679 antibody, AI462438 antibody, ACDP1 antibody, CLP-1 antibody, CGP-39 antibody, GP-39 antibody, SPC-40 antibody, SPS-40 antibody, YKL-40 antibody, HEAB antibody, hClp1 antibody, fa28a12 antibody, wu:fa28a12 antibody, clp1 antibody, cleavage and polyadenylation factor I subunit 1 antibody, CLP1, cleavage and polyadenylation factor I subunit antibody, cyclin and CBS domain divalent metal cation transport mediator 1 antibody, chitinase 3-like 1 (cartilage glycoprotein-39) antibody, cleavage and polyadenylation factor I subunit 1 L homeolog antibody, Clp1 antibody, CNNM1 antibody, CHI3L1 antibody, CLP1 antibody, clp1 antibody, clp1.L antibody
- 背景
-
Description: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a key role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex: phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing, this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA (PubMed:24766809, PubMed:24766810). Its role in tRNA splicing and maturation is required for cerebellar development (PubMed:24766809, PubMed:24766810). Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.
Gene: CLP1
- 分子量
- 48 kDa
- 基因ID
- 10978
- UniProt
- Q92989
- 途径
- Ribonucleoprotein Complex Subunit Organization
-
You are here:
