CITED1 抗体 (Internal Region)
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- 抗原 See all CITED1 抗体
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
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抗原表位
- Internal Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CITED1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- CITED1 Antibody detects endogenous levels of total CITED1.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CITED1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CITED1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
- 别名
- CITED1 (CITED1 产品)
- 别名
- cited1 antibody, fi05d05 antibody, CITED1 antibody, MSG1 antibody, AI316840 antibody, AU019144 antibody, Msg1 antibody, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antibody, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antibody, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antibody, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antibody, cited1 antibody, CITED1 antibody, Cited1 antibody
- 背景
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Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Gene: CITED1
- 分子量
- 20 kDa
- 基因ID
- 4435
- UniProt
- Q99966
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