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CITED1 抗体 (Internal Region)

CITED1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260846
发货至: 中国
  • 抗原 See all CITED1 抗体
    CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
    抗原表位
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 27
    • 18
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 20
    • 8
    克隆类型
    • 20
    • 8
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CITED1 antibody is un-conjugated
    应用范围
    • 27
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    特异性
    CITED1 Antibody detects endogenous levels of total CITED1.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CITED1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CITED1 Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CITED1 (Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 1 (CITED1))
    别名
    CITED1 (CITED1 产品)
    别名
    cited1 antibody, fi05d05 antibody, CITED1 antibody, MSG1 antibody, AI316840 antibody, AU019144 antibody, Msg1 antibody, Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 antibody, Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 antibody, similar to Cbp/p300-interacting transactivator 1 (Melanocyte-specific protein 1) antibody, Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 antibody, cited1 antibody, CITED1 antibody, Cited1 antibody
    背景

    Description: Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling, stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.

    Gene: CITED1

    分子量
    20 kDa
    基因ID
    4435
    UniProt
    Q99966
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