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CHI3L1 抗体 (Internal Region)

CHI3L1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260803
发货至: 中国
  • 抗原 See all CHI3L1 抗体
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    抗原表位
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 43
    • 29
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 41
    • 5
    • 1
    克隆类型
    • 41
    • 5
    • 1
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHI3L1 antibody is un-conjugated
    应用范围
    • 36
    • 15
    • 13
    • 13
    • 10
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    特异性
    CHI3L1 Antibody detects endogenous levels of total CHI3L1.
    预测反应
    Pig,Bovine,Rabbit,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CHI3L1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
    别名
    CHI3L1 (CHI3L1 产品)
    别名
    AW208766 antibody, Brp39 antibody, Gp39 antibody, ASRT7 antibody, CGP-39 antibody, GP-39 antibody, GP39 antibody, HC-gp39 antibody, HCGP-3P antibody, YKL-40 antibody, YKL40 antibody, YYL-40 antibody, hCGP-39 antibody, GP38K antibody, CLP-1 antibody, SPC-40 antibody, SPS-40 antibody, Chil1 antibody, BP40 antibody, MGP-40 antibody, chitinase-like 1 antibody, chitinase 3 like 1 antibody, chitinase 3-like 1 (cartilage glycoprotein-39) antibody, Chil1 antibody, CHI3L1 antibody, Chi3l1 antibody
    物质类
    Viral Protein
    背景

    Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

    Gene: CHI3L1

    分子量
    43kDa
    基因ID
    1116
    UniProt
    P36222
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