CHI3L1 抗体 (Internal Region)
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- 抗原 See all CHI3L1 抗体
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHI3L1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- 特异性
- CHI3L1 Antibody detects endogenous levels of total CHI3L1.
- 预测反应
- Pig,Bovine,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CHI3L1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CHI3L1 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- CHI3L1 (Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1))
- 别名
- CHI3L1 (CHI3L1 产品)
- 别名
- AW208766 antibody, Brp39 antibody, Gp39 antibody, ASRT7 antibody, CGP-39 antibody, GP-39 antibody, GP39 antibody, HC-gp39 antibody, HCGP-3P antibody, YKL-40 antibody, YKL40 antibody, YYL-40 antibody, hCGP-39 antibody, GP38K antibody, CLP-1 antibody, SPC-40 antibody, SPS-40 antibody, Chil1 antibody, BP40 antibody, MGP-40 antibody, chitinase-like 1 antibody, chitinase 3 like 1 antibody, chitinase 3-like 1 (cartilage glycoprotein-39) antibody, Chil1 antibody, CHI3L1 antibody, Chi3l1 antibody
- 物质类
- Viral Protein
- 背景
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Description: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
Gene: CHI3L1
- 分子量
- 43kDa
- 基因ID
- 1116
- UniProt
- P36222
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