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CCRN4L 抗体

CCRN4L 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260565
发货至: 中国
  • 抗原 See all CCRN4L 抗体
    CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))
    适用
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    人, 大鼠, 小鼠
    宿主
    • 33
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    克隆类型
    • 33
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    多克隆
    标记
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    This CCRN4L antibody is un-conjugated
    应用范围
    • 29
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    Western Blotting (WB), ELISA
    特异性
    CCRN4L Antibody detects endogenous levels of total CCRN4L
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CCRN4L
    亚型
    IgG
    Top Product
    Discover our top product CCRN4L Primary Antibody
  • 应用备注
    WB 1:1000-3000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    CCRN4L (CCR4 Carbon Catabolite Repression 4-Like (CCRN4L))
    别名
    CCRN4L (CCRN4L 产品)
    别名
    CCR4L antibody, NOC antibody, AU043840 antibody, Ccr4 antibody, nocturnin antibody, Ccrn4lb antibody, MNOC antibody, ccr4l antibody, noc antibody, MGC85016 antibody, ccrn4l antibody, CCRN4L antibody, nocturnin antibody, nocturnin S homeolog antibody, nocturnin L homeolog antibody, putative nocturnin antibody, NOCT antibody, Noct antibody, noct antibody, noct.S antibody, noct.L antibody, LOC5570471 antibody, CpipJ_CPIJ011434 antibody, Smp_105040 antibody
    背景

    Description: Circadian deadenylase which plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Degrades poly(A) tails of specific target mRNAs leading to their degradation and suppression of translation. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. Plays an important role in favoring adipogenesis over osteoblastogenesis and acts as a key regulator of the adipogenesis/osteogenesis balance. Promotes adipogenesis by activating PPARG transcriptional activity in a deadenylase-independent manner by facilitating its nuclear translocation. Regulates circadian expression of NOS2 in the liver and negatively regulates the circadian expression of IGF1 in the bone. Critical for proper development of early embryos (By similarity).

    Gene: NOCT

    分子量
    48 kDa
    基因ID
    25819
    UniProt
    Q9UK39
    途径
    Ribonucleoprotein Complex Subunit Organization
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