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BAG1 抗体 (N-Term)

BAG1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260189
发货至: 中国
  • 抗原 See all BAG1 抗体
    BAG1 (BCL2-Associated Athanogene (BAG1))
    抗原表位
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 32
    • 18
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 29
    • 8
    克隆类型
    • 29
    • 8
    多克隆
    标记
    • 30
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG1 antibody is un-conjugated
    应用范围
    • 29
    • 14
    • 10
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Bag 1 Antibody detects endogenous levels of total Bag 1.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human Bag 1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product BAG1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    BAG1 (BCL2-Associated Athanogene (BAG1))
    别名
    BAG1 (BAG1 产品)
    别名
    BAG-1 antibody, HAP antibody, RAP46 antibody, Rap46 antibody, Bag-1 antibody, ATBAG1 antibody, BCL-2-associated athanogene 1 antibody, MSG15.15 antibody, MSG15_15 antibody, im:7148830 antibody, si:dkey-216e9.4 antibody, BCL2 associated athanogene 1 antibody, putative bcl2-associated athanogene antibody, BCL2-associated athanogene 1 antibody, Bcl2 associated athanogene 1 antibody, BAG family molecular chaperone regulator 1 antibody, BCL-2-associated athanogene 1 antibody, BAG1 antibody, Smp_005900 antibody, Bag1 antibody, bag-1 antibody, LOC781741 antibody, bag1 antibody
    背景

    Description: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:27474739, PubMed:9873016, PubMed:24318877). Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity (PubMed:12724406). Markedly increases the anti-cell death function of BCL2 induced by various stimuli (PubMed:9305631).

    Gene: BAG1

    分子量
    31 kDa
    基因ID
    573
    UniProt
    Q99933
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