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ATG7 抗体 (N-Term)

Name: ATG7 抗体 (N-Term)
SKU: ABIN6260108
Availability: OutOfStock

ATG7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of 293T lysate using ATG7 antibody.

ABIN6276400 at 1/100 staining Human lymph node tissue by IHC-P.

IHC

2 images

(1 reference)

产品编号 ABIN6260108

发货至: 中国

Datasheet as PDF

抗原 See all ATG7 抗体

ATG7 (ATG7 Autophagy Related 7 (ATG7))
抗原表位
17

15

15

9

6

6

6

6

5

4

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
适用
120

39

27

2

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
108

13

2
兔
Compatible Secondaries
克隆类型
101

22
多克隆
标记
62

9

8

7

6

5

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This ATG7 antibody is un-conjugated
应用范围
102

58

46

26

18

15

14

14

13

9

5

4

3

2

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

特异性

ATG7 Antibody detects endogenous levels of total ATG7.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ATG7, corresponding to a region within N-terminal amino acids.

亚型

IgG

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ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 488

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ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Atto 390

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Li, Li, Zeng, Yang, Liu, Zhang, Song, Yao, Ma, Li, Wang, Wei: "Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis." in: Journal of virology, Vol. 92, Issue 8, (2018) (PubMed).
抗原

ATG7 (ATG7 Autophagy Related 7 (ATG7))

别名

ATG7 (ATG7 产品)

别名

APG7-LIKE antibody, APG7L antibody, GSA7 antibody, D8 antibody, UBA1B antibody, UBE1L antibody, UBE2 antibody, Ube1l antibody, 1300004C08Rik antibody, AO090001000744 antibody, atg7 antibody, 1810013K23Rik antibody, Agp7 antibody, Apg7l antibody, Atg7l antibody, ATAPG7 antibody, ATATG7 antibody, ATG7 antibody, AUTOPHAGY 7 antibody, AUTOPHAGY-RELATED 7 antibody, K15I22.10 antibody, K15I22_10 antibody, autophagy related 7 antibody, ubiquitin like modifier activating enzyme 7 antibody, ubiquitin-like modifier activating enzyme 7 antibody, autophagy-related protein 7 antibody, Autophagy-related protein 7 antibody, Apg7p antibody, ThiF family protein antibody, ubiquitin-like conjugating enzyme Atg7 antibody, ATG7 antibody, UBA7 antibody, Uba7 antibody, ANI_1_3368024 antibody, AOR_1_1338164 antibody, PTRG_02236 antibody, PAAG_00287 antibody, PITG_12537 antibody, atg7 antibody, Atg7 antibody, APG7 antibody

背景

Description: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress. Plays also a key role in the maintenance of axonal homeostasis, the prevention of axonal degeneration, the maintenance of hematopoietic stem cells, the formation of Paneth cell granules, as well as in adipose differentiation.
Gene: ATG7

分子量

78kDa

基因ID

10533

UniProt

O95352

途径

Response to Water Deprivation, Autophagy