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ASIP 抗体 (Internal Region)

ASIP 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260077
发货至: 中国
  • 抗原 See all ASIP 抗体
    ASIP (Agouti Signaling Protein (ASIP))
    抗原表位
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 24
    • 2
    宿主
    • 25
    克隆类型
    • 25
    多克隆
    标记
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASIP antibody is un-conjugated
    应用范围
    • 15
    • 7
    • 5
    • 4
    • 2
    ELISA, Western Blotting (WB)
    特异性
    ASIP Antibody detects endogenous levels of total ASIP.
    预测反应
    Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human ASIP, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product ASIP Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    ASIP (Agouti Signaling Protein (ASIP))
    别名
    ASIP (ASIP 产品)
    别名
    AGSW antibody, AGTI antibody, AGTIL antibody, ASP antibody, SHEP9 antibody, ASIP antibody, AA960621 antibody, AI256638 antibody, D8Ertd580e antibody, PAR-3 antibody, Par3 antibody, Pard3a antibody, agouti signaling protein antibody, par-3 family cell polarity regulator antibody, ASIP antibody, Asip antibody, asip antibody, Pard3 antibody
    背景

    Description: Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

    Gene: ASIP

    分子量
    14 kDa
    基因ID
    434
    UniProt
    P42127
    途径
    Cell-Cell Junction Organization, Feeding Behaviour
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