ARF1 抗体 (Internal Region)
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- 抗原 See all ARF1 抗体
- ARF1 (ADP-Ribosylation Factor 1 (ARF1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ARF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- ARF1 Antibody detects endogenous levels of total ARF1.
- 预测反应
- Pig,Zebrafish,Bovine,Sheep,Rabbit,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human ARF1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ARF1 Primary Antibody
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- 应用备注
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- ARF1 (ADP-Ribosylation Factor 1 (ARF1))
- 别名
- ARF1 (ARF1 产品)
- 别名
- wu:fb33e02 antibody, wu:fb78h01 antibody, arf2 antibody, arf-1 antibody, MGC52573 antibody, ADP-RIBOSYLATION FACTOR antibody, ADP-RIBOSYLATION FACTOR 1A antibody, ADP-ribosylation factor 1 antibody, ATARF antibody, ATARF1 antibody, ATARFA1A antibody, F28C11.12 antibody, ARF1 antibody, arf1 antibody, ADP ribosylation factor 1 antibody, ADP-ribosylation factor 1 antibody, ADP ribosylation factor 1 L homeolog antibody, ADP ribosylation factor 5 L homeolog antibody, ADP ribosylation factor 1 pseudogene antibody, adp-ribosylation factor 1 antibody, ARF1 antibody, Arf1 antibody, arf1 antibody, arf1.L antibody, arf5.L antibody, NCU08340 antibody, TRIADDRAFT_63238 antibody, PAAG_08805 antibody, LOC100280562 antibody, LOC100280918 antibody, LOC474591 antibody, CLUG_01013 antibody
- 背景
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Description: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity, the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long-term depression (LTD).
Gene: ARF1
- 分子量
- 20 kDa
- 基因ID
- 375
- UniProt
- P84077
- 途径
- Transition Metal Ion Homeostasis, Inositol Metabolic Process
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