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PRKAB1 抗体

PRKAB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6259918
发货至: 中国
  • 抗原 See all PRKAB1 抗体
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    适用
    • 114
    • 100
    • 97
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 136
    • 9
    克隆类型
    • 128
    • 17
    多克隆
    标记
    • 51
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 1
    This PRKAB1 antibody is un-conjugated
    应用范围
    • 80
    • 65
    • 65
    • 48
    • 28
    • 22
    • 15
    • 15
    • 10
    • 7
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    AMPK β1 Antibody detects endogenous levels of total AMPK β1
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human AMPK beta1
    亚型
    IgG
    Top Product
    Discover our top product PRKAB1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))
    别名
    AMPK beta1 (PRKAB1 产品)
    别名
    AMPK antibody, HAMPKb antibody, 1300015D22Rik antibody, AU021155 antibody, E430008F22 antibody, MGC82489 antibody, prkab1 antibody, wu:fk93d05 antibody, wu:fw87e09 antibody, zgc:56652 antibody, zgc:76975 antibody, zgc:92228 antibody, protein kinase AMP-activated non-catalytic subunit beta 1 antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit S homeolog antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, b antibody, protein kinase, AMP-activated, beta 1 non-catalytic subunit, a antibody, PRKAB1 antibody, Prkab1 antibody, prkab1.S antibody, prkab1 antibody, prkab1b antibody, prkab1a antibody
    背景

    Description: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton, probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

    Gene: PRKAB1

    分子量
    38kDa
    基因ID
    5564
    UniProt
    Q9Y478
    途径
    AMPK Signaling, Warburg Effect
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