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eIF4EBP1 抗体 (Internal Region)

Name: eIF4EBP1 抗体 (Internal Region)
SKU: ABIN6259647
Availability: OutOfStock

EIF4EBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of 4E-BP1 expression in EGF treated MDA-MB-435 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.

ABIN6269351 at 1/100 staining Human prostate tissue by IHC-P.

IHC

IF/ICC

Western blot analysis of extracts from Myeloma cells, using 4E-BP1 Antibody.

4 images

产品编号 ABIN6259647

发货至: 中国

Datasheet as PDF

抗原 See all eIF4EBP1 (EIF4EBP1) 抗体

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
抗原表位
29

28

26

21

16

15

12

11

9

8

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5

5

5

4

4

3

2

2

2

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2

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2

2

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1

1

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1

1

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1

1

1

1

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1
Internal Region
适用
231

165

121

21

14

7

6

5

4

3

2

2

1

1

1
人, 小鼠, 大鼠
宿主
250

13

4
兔
Compatible Secondaries
克隆类型
231

38
多克隆
标记
115

25

18

11

10

10

10

9

9

9

7

6

6

6

6

6

4

1

1
This eIF4EBP1 antibody is un-conjugated
应用范围
211

87

84

67

66

46

30

23

16

12

10

8

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

特异性

4E-BP1 Antibody detects endogenous levels of total 4E-BP1.

预测反应

Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human 4E-BP1, corresponding to a region within the internal amino acids.

亚型

IgG

Top Product

Discover our top product EIF4EBP1 Primary Antibody
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibody
EIF4EBP1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr37), (pThr46) antibody
EIF4EBP1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibody
EIF4EBP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 适用: 人 WB, IHC, ELISA, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1E2E7 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibody
EIF4EBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) antibody
EIF4EBP1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4F3-H2 unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr36) antibody
EIF4EBP1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-111) antibody
EIF4EBP1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibody
EIF4EBP1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (Thr69) antibody
EIF4EBP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))

别名

EIF4EBP1 (EIF4EBP1 产品)

别名

4E-BP1 antibody, 4EBP1 antibody, BP-1 antibody, PHAS-I antibody, 4e-bp1 antibody, AA959816 antibody, 153432_at antibody, 43-BP antibody, 4E-BP antibody, 4EBP antibody, 4e-bp antibody, 4eBP antibody, 4ebp antibody, BcDNA.HL08053 antibody, BcDNA:HL08053 antibody, CG8846 antibody, CT8705 antibody, Dm 4E-BP antibody, Dmel\\CG8846 antibody, Phas1 antibody, Thor/EIF4EBP antibody, anon-WO0172774.158 antibody, d4E-BP antibody, d4E-BP1 antibody, d4EBP antibody, d4e-bp antibody, d4eBP antibody, dthor antibody, eIF4E-BP antibody, l(2)06270 antibody, l(2)k07736 antibody, l(2)k13517 antibody, pp20 antibody, thor antibody, EIF4EBP1 antibody, fc04h09 antibody, wu:fc04h09 antibody, zgc:64137 antibody, eukaryotic translation initiation factor 4E binding protein 1 antibody, CG8846 gene product from transcript CG8846-RA antibody, EIF4EBP1 antibody, Eif4ebp1 antibody, Thor antibody, eif4ebp1 antibody

背景

Description: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
Gene: EIF4EBP1

分子量

18kDa

基因ID

1978

UniProt

Q13541

途径

MAPK Pathway, PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Regulation of Cell Size, BCR Signaling