SLC24A6 抗体 (C-Term)
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- 抗原 See all SLC24A6 抗体
- SLC24A6 (Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC24A6 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- SLC24A6 Antibody detects endogenous levels of total SLC24A6.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human SLC24A6, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product SLC24A6 Primary Antibody
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anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) antibody
SLC24A6 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) antibodySLC24A6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) (AA 468-517) antibodySLC24A6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) (AA 494-543) antibodySLC24A6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) (Middle Region) antibodySLC24A6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6) antibodySLC24A6 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- SLC24A6 (Solute Carrier Family 24 (Sodium/potassium/calcium Exchanger), Member 6 (SLC24A6))
- 别名
- SLC8B1 (SLC24A6 产品)
- 别名
- slc24a6 antibody, NCKX6 antibody, NCLX antibody, SLC24A6 antibody, AF261233 antibody, Slc24a6 antibody, solute carrier family 8 member B1 antibody, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 antibody, solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 S homeolog antibody, SLC8B1 antibody, slc8b1 antibody, Slc8b1 antibody, slc8b1.S antibody
- 背景
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Description: Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion (PubMed:20018762, PubMed:22829870, PubMed:23056385, PubMed:24898248, PubMed:28219928). Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity). Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses (PubMed:23056385). Required for store-operated Ca2+ entry (SOCE) and Ca2+ release-activated Ca2+ (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity (PubMed:28219928). Involved in B-lymphocyte chemotaxis (By similarity). Able to transport Ca2+ in exchange of either Li+ or Na+, explaining how Li+ catalyzes Ca2+ exchange (PubMed:15060069). In contrast to other members of the family its function is independent of K+ (PubMed:15060069).
Gene: SLC8B1
- 分子量
- 60 kDa
- 基因ID
- 80024
- UniProt
- Q6J4K2
- 途径
- Carbohydrate Homeostasis
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