NEIL3 抗体 (C-Term)
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- 抗原 See all NEIL3 抗体
- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEIL3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- NEIL3 Antibody detects endogenous levels of total NEIL3.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human NEIL3, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product NEIL3 Primary Antibody
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anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 2-187) antibody
NEIL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 292-320) antibodyNEIL3 适用: 人 WB 宿主: 兔 Polyclonal RB40413 unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
- 别名
- NEIL3 (NEIL3 产品)
- 别名
- RGD1310562 antibody, NEIL3 antibody, zgc:103553 antibody, neil3 antibody, MAC12.12 antibody, MAC12_12 antibody, FGP2 antibody, FPG2 antibody, NEI3 antibody, hFPG2 antibody, hNEI3 antibody, AI449477 antibody, BC034753 antibody, C85903 antibody, nei-like DNA glycosylase 3 antibody, nei like DNA glycosylase 3 antibody, GRF zinc finger / Zinc knuckle protein antibody, nei-like DNA glycosylase 3 L homeolog antibody, nei like 3 (E. coli) antibody, Neil3 antibody, NEIL3 antibody, neil3 antibody, AT5G13920 antibody, neil3.L antibody
- 背景
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Description: DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
Gene: NEIL3
- 分子量
- 68 kDa
- 基因ID
- 55247
- UniProt
- Q8TAT5
- 途径
- DNA Damage Repair
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