POU4F1 抗体 (Internal Region)
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- 抗原 See all POU4F1 抗体
- POU4F1 (POU Domain, Class 4, Transcription Factor 1 (POU4F1))
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抗原表位
- Internal Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This POU4F1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- POU4F1 Antibody detects endogenous levels of total POU4F1.
- 预测反应
- Pig,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human POU4F1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product POU4F1 Primary Antibody
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anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) (AA 325-419) antibody
POU4F1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) (AA 331-420) antibodyPOU4F1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7B4 unconjugated
anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) (AA 258-419) antibodyPOU4F1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) antibodyPOU4F1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) (C-Term) antibodyPOU4F1 适用: 人, 小鼠, 大鼠, Pig, 犬, 斑马鱼, 豚鼠, 兔, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-POU Domain, Class 4, Transcription Factor 1 (POU4F1) (C-Term) antibodyPOU4F1 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 豚鼠, 兔, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- POU4F1 (POU Domain, Class 4, Transcription Factor 1 (POU4F1))
- 别名
- POU4F1 (POU4F1 产品)
- 别名
- BRN3A antibody, Oct-T1 antibody, RDC-1 antibody, brn-3A antibody, POU4F1 antibody, Brn-3a antibody, Brn-3 antibody, Brn-3.0 antibody, Brn3 antibody, Brn3.0 antibody, Brn3a antibody, E130119J07Rik antibody, brn3.0 antibody, brn3a antibody, brn3a-A antibody, oct-t1 antibody, rdc-1 antibody, POU class 4 homeobox 1 antibody, POU domain, class 4, transcription factor 1 antibody, POU class 4 homeobox 1 L homeolog antibody, POU4F1 antibody, Pou4f1 antibody, pou4f1 antibody, Tsp_01181 antibody, pou4f1.L antibody
- 背景
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Description: Multifunctional transcription factor with different regions mediating its different effects. Acts by binding (via its C-terminal domain) to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Regulates the expression of specific genes involved in differentiation and survival within a subset of neuronal lineages. It has been shown that activation of some of these genes requires its N-terminal domain, maybe through a neuronal-specific cofactor. Ativates BCL2 expression and protects neuronal cells from apoptosis (via the N-terminal domain). Induces neuronal process outgrowth and the coordinate expression of genes encoding synaptic proteins. Exerts its major developmental effects in somatosensory neurons and in brainstem nuclei involved in motor control. Stimulates the binding affinity of the nuclear estrogene receptor ESR1 to DNA estrogen response element (ERE), and hence modulates ESR1-induced transcriptional activity. May positively regulate POU4F2 and POU4F3. Regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Plays a role in TNFSF11-mediated terminal osteoclast differentiation. Negatively regulates its own expression interacting directly with a highly conserved autoregulatory domain surrounding the transcription initiation site.
Gene: POU4F1
- 分子量
- 42 kDa
- 基因ID
- 5457
- UniProt
- Q01851
- 途径
- Feeding Behaviour
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