EIF3D 抗体 (Internal Region)
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- 抗原 See all EIF3D 抗体
- EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))
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抗原表位
- Internal Region
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF3D antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- EIF3D Antibody detects endogenous levels of total EIF3D.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human EIF3D, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product EIF3D Primary Antibody
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anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) (AA 1-240) antibody
EIF3D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) antibodyEIF3D 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) antibodyEIF3D 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) antibodyEIF3D 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) (AA 500-550) antibodyEIF3D 适用: 人, 小鼠, 大鼠, 斑马鱼, 猴, 鱼, Macaque WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) (AA 124-173) antibodyEIF3D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼, 猴, Pig, 小鸡, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) antibodyEIF3D 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) (AA 101-150) antibodyEIF3D 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D) antibodyEIF3D 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))
- 别名
- EIF3D (EIF3D 产品)
- 别名
- eif3s7 antibody, eIF3d antibody, DDBDRAFT_0217568 antibody, DDBDRAFT_0219927 antibody, DDB_0217568 antibody, DDB_0219927 antibody, EIF3S7 antibody, An15g03780 antibody, AO090026000811 antibody, eIF3-p66 antibody, eIF3-zeta antibody, 66/67kDa antibody, AA407891 antibody, Eif3s7 antibody, eIF3p66 antibody, wu:fb12a03 antibody, zgc:64097 antibody, eukaryotic translation initiation factor 3 subunit D antibody, eukaryotic translation initiation factor 3 subunit 7 antibody, eukaryotic initiation factor antibody, eIF-3 zeta antibody, eukaryotic translation initiation factor 3, subunit D antibody, translation initiation factor eIF-3 subunit 7 antibody, eukaryotic translation initiation factor 3 subunit D S homeolog antibody, Eukaryotic translation initiation factor 3 subunit D antibody, eif3d antibody, EIF3D antibody, eIF3-S7 antibody, ANI_1_540134 antibody, AOR_1_1456014 antibody, PTRG_07832 antibody, VDBG_06053 antibody, PGTG_10613 antibody, Tsp_00484 antibody, Eif3d antibody, eif3d.S antibody, eif-3.D antibody
- 背景
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Description: mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs (PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:18599441, PubMed:25849773). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). In the eIF-3 complex, EIF3D specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs (PubMed:27462815).
Gene: EIF3D
- 分子量
- 64 kDa
- 基因ID
- 8664
- UniProt
- O15371
- 途径
- Ribonucleoprotein Complex Subunit Organization
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