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Ube2t 抗体 (Internal Region)

Ube2t 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258234
发货至: 中国
  • 抗原 See all Ube2t 抗体
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    抗原表位
    • 9
    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 39
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 35
    • 3
    • 1
    克隆类型
    • 36
    • 3
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ube2t antibody is un-conjugated
    应用范围
    • 28
    • 26
    • 6
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    UBE2T Antibody detects endogenous levels of total UBE2T.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human UBE2T, corresponding to a region within the internal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product Ube2t Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
    别名
    UBE2T (Ube2t 产品)
    别名
    PIG50 antibody, UBE2T antibody, 2700084L22Rik antibody, C80607 antibody, RGD1310816 antibody, hspc150 antibody, wu:fj86h11 antibody, zgc:153687 antibody, ubiquitin conjugating enzyme E2 T antibody, ubiquitin-conjugating enzyme E2T antibody, ubiquitin conjugating enzyme E2T S homeolog antibody, ubiquitin-conjugating enzyme E2T (putative) antibody, UBE2T antibody, Ube2t antibody, ube2t.S antibody, ube2t antibody
    背景

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784, PubMed:28437106). Also mediates monoubiquitination of FANCL and FANCI (PubMed:16916645, PubMed:17938197, PubMed:19111657, PubMed:19589784). May contribute to ubiquitination and degradation of BRCA1 (PubMed:19887602). In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination (PubMed:20061386).

    Gene: UBE2T

    分子量
    22 kDa
    基因ID
    29089
    UniProt
    Q9NPD8
    途径
    Chromatin Binding
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